Disodium cromoglycate in exercise-induced asthma.

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Effect of disodium cromoglycate on exercise-induced asthma.

In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.

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Disodium cromoglycate in the prevention of induced asthma.

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Comparison of actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction in childhood asthma.

Ketotifen (Zaditen), a benzocycloheptathiophene derivative, is a new oral agent for treating asthma, with action similar in some respects to that of sodium cromoglycate. It is well established that sodium cromoglycate protects against antigen challenge by inhibiting the release of chemical mediators from mast cells. It also inhibits exerciseinduced bronchoconstriction and has bronchodilator pro...

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Sodium cromoglycate and ipratropium bromide in exercise-induced asthma.

In thirteen patients with extrinsic asthma the effects of placebo, sodium cromoglycate, ipratropium bromide, and ipratropium bromide plus sodium cromoglycate were studied in a random double-blind fashion to assess their inhibitory action in exercise-induced asthma (EIA). Exercise testing consisted of steady state running on an inclined treadmill for up to eight minutes. In eight of the 13 patie...

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Change in osmolarity of disodium cromoglycate solution and protection against exercise-induced bronchospasm in children with asthma.

It has been suggested that osmolarity and/or nebulizer output may affect the protective effects of disodium cromoglycate (DSCG) in asthma. The aim of this study was to evaluate the influence of osmolarity of the DSCG solution on exercise-induced bronchospasm (EIB) in children with bronchial asthma. A jet nebulizer was used for DSCG inhalation in Study 1 and an ultrasonic nebulizer in Study 2. T...

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ژورنال

عنوان ژورنال: BMJ

سال: 1969

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5663.177